NKCC1 Does Not Accumulate Chloride in Developing Retinal Neurons
نویسندگان
چکیده
منابع مشابه
NKCC1 does not accumulate chloride in developing retinal neurons.
GABA excites immature neurons due to their relatively high intracellular chloride concentration. This initial high concentration is commonly attributed to the ubiquitous chloride cotransporter NKCC1, which uses a sodium gradient to accumulate chloride. Here we tested this hypothesis in immature retinal amacrine and ganglion cells. Western blotting detected NKCC1 at birth and its expression firs...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2007
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.00288.2007